The NICE guidelines for Type 2 diabetes (NG28) 1. Dual First-Line Therapy The "Metformin-only" start is largely a thing of the past. • The New Standard: Most newly diagnosed patients should now be started on Metformin AND an SGLT-2 inhibitor (e.g., dapagliflozin or empagliflozin) together. • Why? Evidence shows that starting SGLT-2 inhibitors early protects the heart and kidneys regardless of your initial HbA1c levels. • Metformin Change: NICE now recommends modified-release (slow-release) metfo