The factors that govern the timing and duration of sleep and wakefulness continue to be a focal point of vigorous research within the scientific community. Nearly four decades ago, the two-process ...

Sleep and wakefulness are complex processes that require a substantial portion of brain circuitry to effectively regulate. These are not passive processes but complexly managed states that have to be ...

In a paper published in npj Biological Timing and Sleep, researchers analyzed the mathematical structure of the two-process model (2PM) of sleep regulation, which was first proposed in the 1980s. The ...

The 2PM explains how our sleep patterns are shaped by two factors - a pressure to sleep that builds the longer we are awake and diminishes during sleep, and the near 24-hour rhythm of our internal ...