Substance P, an endogenous neuropeptide, and its corresponding receptor, the Neurokinin-1 Receptor (NK1R), play a central role in a host of physiological functions including nociception, inflammation, ...

The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the coronavirus disease 2019 (COVID-19) pandemic. Common post-COVID-19 symptoms include fatigue, muscle ...

US FDA approves Vanda Pharma’s Nereus, an oral NK-1 receptor antagonist for prevention of vomiting induced by motion: Washington Friday, January 2, 2026, 15:00 Hrs [IST] Vanda P ...

G protein-coupled receptors (GPCRs) are a large family of proteins that regulate many processes in the body and are the target of one third of clinically used drugs. A subset of these receptors plays ...

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells. Researchers have now been able to show for the first time how an important inhibitor binds to the receptor.