An understanding of the origin and dynamics of heritable genetic variation within classical animal breeding programs is needed to provide the context for understanding the contributions and concerns ...

This work delineates how Setd2-mediated epigenetic reprogramming overcomes developmental barriers in cloned embryos. Comparative analysis revealed that SCNT embryos exhibit excessive H3K4me3 and ...

Generating gametes from nonreproductive tissues could help overcome infertility. Previous studies have successfully transformed stem cells into viable oocytes through cellular reprogramming.