A viral inner nuclear membrane–sorting motif sequence (INM-SM) was used to identify proteins that recognize integral membrane proteins destined for the INM. Herein we describe importin-α-16, a ...

The Wnt/beta-catenin signaling pathway regulates stem cell renewal and cell proliferation by controlling DNA transcription, and its abnormal activation plays a role in many cancers. Now, scientists at ...

This is a preview. Log in through your library . Abstract Signal transducer and activator of transcription (STAT)3 is a member of a family of DNA-binding factors that function to induce expression of ...

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell ...

Although scientists appreciate that the nuclear pore complex (NPC) is more than a complex structure, and that it is, in fact, an intricate machine, they are still trying to work out all the ...

SOUTH BEND, Ind. (WNDU) - A South Bend coffee business that’s gained a lot of recognition for its cup of joe will soon be brewing up something else. Joe Luten, co-founder and president of Importin’ ...

SOUTH BEND, Ind. (WNDU) - New details on a South Bend business that’s making Michiana the home for Ethiopian Coffee. We first learned about Importin Joes back in 2020 when founder, Joseph Luten, was ...

During his years of travel, Joseph Luten said he was on a mission to find what connects humans. “I was looking for that human trait, that gene that just connected everyone, and honestly, everywhere I ...

You’d think that most people who’ve been working tirelessly to gain a foothold in the higher-end coffee market would be hopelessly passionate about the inspiring aspects of a perfect cup of joe. But ...