Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes. These droplet-like dynamic assemblies control the way in which DNA is turned into ...

How does our DNA store the massive amount of information needed to build a human being? And what happens when it's stored incorrectly? Jesse Dixon, MD, Ph.D., has spent years studying the way this ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results ...